Analgesic compositions comprising anti-epileptic compounds and methods of using same
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United States of America Patent
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Sep 13, 2005
Grant Date -
Apr 3, 2003
app pub date -
Feb 13, 2002
filing date -
Sep 8, 1997
priority date (Note) -
Expired
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Abstract
The present invention is directed to novel combinations of anti-epileptic compounds that demonstrate pain alleviating properties, with compounds selected from the group consisting of analgesics, NMDA receptor antagonists, and NSAIDs and pharmaceutical compositions comprising same. It has been discovered that the administration of anti-epileptic compounds that demonstrate pain alleviating properties in these novel combinations results in an improved reduction in the frequency and severity of pain. It is also believed that the incidence of unwanted side effects can be reduced by these novel combinations in comparison to using higher doses of a single agent treatment to achieve a similar therapeutic effect. The present invention is also directed to methods of using effective amounts of the novel pharmaceutical compositions to treat pain in mammals.
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