Method of fabricating a microfluidic delivery system

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United States of America Patent

PATENT NO 6949253
APP PUB NO 20050045592A1
SERIAL NO

10635633

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Abstract

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An implantable biocompatible microchip drug delivery substrate is coated with a thin film of ultra-nanocrystalline diamond; assuring that the device is biocompatible and impermeably sealed, to prevent the substrate from being dissolved by the living tissue and to protect the drugs from premature release or undesired reaction with the body fluids. The coating is selectively patterned by doping to create electrically conductive areas that can be used as an electrically activated release mechanism for drug delivery. The conformal ultra-nanocrystalline diamond coating uniformly covers the device, providing relief from sharp edges and producing a strong, uniformly thick impermeable coating around sharp edges and on high aspect-ratio parts. The ultra-nanocrystalline diamond coating provides a conformal coating on the biocompatible device, which is of approximately uniform thickness around sharp corners and on high aspect-ratio parts. The conformal nature of the coating assures impermeability and strength despite the presence of difficult to coat shapes.

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Patent Owner(s)

Patent OwnerAddress
SECOND SIGHT MEDICAL PRODUCTS INC12744 SAN FERNANDO ROAD BUILDING 3 SYLMAR CA 91342

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Greenberg, Robert J Los Angeles, CA 291 7232
Mech, Brian V Sherman Oaks, CA 54 1953

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