US Patent No: 6,955,661

Number of patents in Portfolio can not be more than 2000

Expandable fluoropolymer device for delivery of therapeutic agents and method of making

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Abstract

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A radially expandable fluid delivery device for delivering a fluid to a treatment site within the body is disclosed. The fluid delivery device is constructed of a microporous, biocompatible fluoropolymer material having a microstructure that can provide a controlled, uniform, low-velocity fluid distribution through the walls of the fluid delivery device to effectively deliver fluid to the treatment site without damaging tissue proximate the walls of the device. The fluid delivery device includes a tubular member defined by a wall having a thickness transverse to the longitudinal axis of the tubular member and extending between an inner and an outer surface. The wall is characterized by a microstructure of nodes interconnected by fibrils. The tubular member is deployable from a first, reduced diameter configuration to a second, increased diameter configuration upon the introduction of a pressurized fluid to the lumen. The tubular member includes at least one microporous portion having a porosity sufficient for the pressurized fluid to permeate through the wall. Substantially all of the nodes within the microporous portion are oriented such that spaces between the nodes form micro-channels extending from the inner surface-to the outer surface of the wall.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ATRIUM MEDICAL CORPORATIONHUDSON, NH79

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gingras, Peter H Windham, NH 13 385
Herweck, Steve A Nashua, NH 122 2357
Karwoski, Theodore Hollis, NH 123 2750
Martakos, Paul Pelham, NH 106 1805

Cited Art Landscape

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (10)
4,994,033 Intravascular drug delivery dilatation catheter 380 1989
5,254,089 Medication dispensing balloon catheter 161 1992
5,397,307 Drug delivery PTCA catheter and method for drug delivery 157 1993
5,415,636 Dilation-drug delivery catheter 89 1994
5,514,092 Drug delivery and dilatation-drug delivery catheters in a rapid exchange configuration 131 1994
5,500,181 Shrinking balloon catheter having nonlinear compliance curve 55 1995
5,512,051 Slip-layered catheter balloon 132 1995
5,782,797 Therapeutic infusion device 79 1996
6,358,227 Dilatation catheter balloon made from pen based homopolymer or random copolymer 33 1997
6,013,055 Catheter balloon having selected folding characteristics 64 1997
 
CORDIS CORPORATION (10)
5,049,132 Balloon catheter for delivering therapeutic agents 380 1990
5,213,576 Therapeutic porous balloon catheter 266 1991
5,236,659 Tailoring expansion properties of balloons for medical devices 49 1992
5,318,531 Infusion balloon catheter 117 1992
5,405,472 Method of making infusion balloon catheter 45 1993
5,823,996 Infusion balloon catheter 77 1996
5,882,335 Retrievable drug delivery stent 145 1996
5,833,659 Infusion balloon catheter 77 1996
5,709,653 Photodynamic therapy balloon catheter with microporous membrane 53 1996
5,902,266 Method for delivering a liquid solution to the interior wall surface of a vessel 126 1998
 
ADVANCED CARDIOVASCULAR SYSTEMS, INC. (6)
4,692,200 Self-venting balloon dilatation catheter and method 23 1986
4,877,031 Steerable perfusion dilatation catheter 226 1988
5,021,044 Catheter for even distribution of therapeutic fluids 222 1989
4,968,307 Catheter for uniform distribution of therapeutic fluids 92 1989
4,968,306 Intravascular catheter having an adjustable length infusion section to delivery therapeutic fluid 101 1989
5,707,385 Drug loaded elastic membrane and method for delivery 266 1994
 
BOSTON SCIENTIFIC CORPORATION (6)
5,533,516 Sample collection 24 1995
5,868,719 Drug delivery balloon catheter device 56 1997
5,843,033 Multiple hole drug delivery balloon 73 1997
5,860,954 Multiple hole drug delivery balloon 39 1997
6,364,856 Medical device with sponge coating for controlled drug release 145 1998
6,135,982 Balloon catheterization 29 1999
 
W. L. GORE & ASSOCIATES, INC. (6)
5,752,934 Balloon catheter device 83 1995
5,868,704 Balloon catheter device 85 1996
6,120,477 Balloon catheter device 161 1997
5,843,069 Implantable containment apparatus for a therapeutical device and method for loading and reloading the device therein 145 1997
6,139,572 Delivery system for intraluminal vascular grafts 71 1998
6,375,637 Catheter balloon having a controlled failure mechanism 44 1999
 
CARDIOVASCULAR DYNAMICS, INC. (5)
5,295,962 Drug delivery and dilatation catheter 134 1992
5,344,402 Low profile perfusion catheter 108 1993
5,421,826 Drug delivery and dilatation catheter having a reinforced perfusion lumen 73 1994
5,542,926 Low profile perfusion catheter 31 1994
5,522,800 Low profile perfusion catheter 30 1994
 
SYNECTIC VENTURES I LLC (4)
5,071,424 Catheter atherotome 96 1991
5,211,651 Catheter atherotome 89 1991
5,156,610 Catheter atherotome 86 1991
5,282,484 Method for performing a partial atherectomy 122 1992
 
VENTION MEDICAL ADVANCED COMPONENTS, INC. (4)
5,286,254 Drug delivery apparatus and method 381 1992
5,458,568 Porous balloon for selective dilatation and drug delivery 203 1993
5,628,730 Phoretic balloon catheter with hydrogel coating 339 1994
5,807,306 Polymer matrix drug delivery apparatus 293 1994
 
LOCALMED, INC. (3)
5,279,565 Intravascular treatment apparatus and method 177 1993
5,336,178 Intravascular catheter with infusion array 153 1993
5,810,767 Method and apparatus for pressurized intraluminal drug delivery 44 1996
 
ATRIUM MEDICAL CORPORATION (2)
5,433,909 Method of making controlled porosity expanded polytetrafluoroethylene products 58 1993
5,474,824 Process for expanding polytetrafluoroethylene and products produced thereby 40 1994
 
COOK INCORPORATED (2)
4,637,396 Balloon catheter 153 1984
5,015,232 Decompression enteroclysis balloon catheter 41 1989
 
FOGARTY, THOMAS J. (2)
4,721,507 Shear force gauge and method and apparatus for limiting embolectomy shear force 22 1986
4,762,130 Catheter with corkscrew-like balloon 360 1987
 
MEDTRONIC AVE, INC. (2)
4,820,349 Dilatation catheter with collapsible outer diameter 314 1987
5,500,180 Method of making a distensible dilatation balloon using a block copolymer 113 1992
 
SUMITOMO ELECTRIC INDUSTRIES, LTD. (2)
4,229,838 Vascular prosthesis having a composite structure 87 1978
4,713,070 Porous structure of polytetrafluoroethylene and process for production thereof 88 1986
 
Adams and Reese LLP (1)
4,714,460 Methods and systems for retrograde perfusion in the body for curing it of the disease or immume deficiency 173 1986
 
ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (1)
5,306,250 Method and apparatus for intravascular drug delivery 174 1992
 
AKAMAI TECHNOLOGIES, INC. (1)
2009/0132,648 CONTENT DELIVERY AND GLOBAL TRAFFIC MANAGEMENT NETWORK SYSTEM 25 2009
 
Angiobrade Partners (1)
4,650,466 Angioplasty device 708 1985
 
APPLIED MEDICAL RESOURCES CORPORATION (1)
5,192,290 Embolectomy catheter 111 1990
 
ATRIONIX, INC. (1)
6,500,174 Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member 114 1999
 
BARD CONNAUGHT (1)
6,048,332 Dimpled porous infusion balloon 72 1998
 
BECTON, DICKINSON AND COMPANY (1)
4,714,461 Catheter assembly with air purging feature 12 1985
 
BRACK GILLIUM HATTLER (1)
4,406,656 Venous catheter having collapsible multi-lumens 307 1981
 
C.R. BARD, INC. (1)
5,087,244 Catheter and method for locally applying medication to the wall of a blood vessel or other body lumen 283 1990
 
CARDIO VASCULAR DYNAMICS (1)
5,368,566 Delivery and temporary stent catheter having a reinforced perfusion lumen 149 1992
 
Cardiovascular Designs, Inc. (1)
5,087,247 Balloon perfusion catheter 83 1990
 
CEDARS-SINAI MEDICAL CENTER (1)
5,112,305 Catheter device for intramural delivery of therapeutic agents 165 1990
 
DON MICHAEL INTERNATIONAL, LLC (1)
5,176,638 Regional perfusion catheter with improved drug delivery control 119 1991
 
Hanover; George (1)
4,327,721 Endotracheal tube with topical agent delivery system and method of using the same 86 1979
 
HOWA TEXTILE INDUSTRY CO., LTD. (1)
6,386,626 Sunshade for vehicle sunroof 6 2000
 
KLEVSKY NAUCHNO-ISSLEDOVATELSKY INSTITUT NEIROKHIRUGII (1)
5,041,090 Occluding device 72 1989
 
LIFESHIELD SCIENCES LLC (1)
6,364,903 Polymer coated stent 139 1999
 
MEDTRONIC, INC. (1)
4,711,251 Body implantable lead 316 1983
 
NEUROPERFUSION, INC. (1)
4,850,969 Retroperfusion catheter and tip construction for use therewith 125 1988
 
PDT Cardiovascular, Inc. (1)
5,456,661 Catheter with thermally stable balloon 53 1994
 
Schneider (Europe) A.G. (1)
4,573,966 Method and apparatus for removing and/or enlarging constricted areas in vessels conducting body fluids 297 1982
 
SCHNEIDER (USA) INC. (1)
5,772,632 Dilation-drug delivery catheter 40 1997
 
Schneider Europe (1)
5,098,381 Catheter for recanalizing constricted vessels 53 1991
 
SHERWOOD SERVICES AG (1)
5,269,755 Catheter with outer membrane medicament delivery system 86 1992
 
SILICON VALLEY BANK (1)
4,744,366 Concentric independently inflatable/deflatable multiple diameter balloon angioplasty catheter systems and method of use 200 1986
 
ST. ELIZABETH'S MEDICAL CENTER, INC. (1)
6,369,039 High efficiency local drug delivery 98 1998
 
TERUMO KABUSHIKI KAISHA (1)
4,832,688 Catheter for repair of blood vessel 208 1987
 
The Beth Israel Hospital Association (1)
4,799,479 Method and apparatus for angioplasty 292 1987
 
TRACKS, INC. (1)
5,112,347 Embolectomy catheter, and method of operating same 71 1991
 
WAYNE STATE UNIVERSITY (1)
5,199,951 Method of drug application in a transporting medium to an arterial wall injured during angioplasty 110 1991
 
XRT CORP. (1)
5,713,853 Methods for treating thrombosis 127 1995
 
YAMAHA HATSUDOKI KABUSHIKI KAISHA (1)
5,928,193 Balloon catheterization 5 1997
 
Other [Check patent profile for assignment information] (10)
4,338,942 Dilatation catherter apparatus 170 1980
4,437,856 Peritoneal catheter device for dialysis 99 1981
4,417,576 Double-wall surgical cuff 174 1982
4,423,725 Multiple surgical cuff 437 1982
4,636,195 Method and apparatus for removing arterial constriction 230 1985
4,693,243 Conduit system for directly administering topical anaesthesia to blocked laryngeal-tracheal areas 123 1986
4,824,436 Method for the prevention of restenosis 241 1987
5,100,383 Catheters permitting controlled diffusion 16 1990
5,232,444 Dilatation catheter 266 1991
5,499,995 Body passageway closure apparatus and method of use 131 1994

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
BOSTON SCIENTIFIC SCIMED, INC. (41)
7,470,252 Expandable multi-port therapeutic delivery system 20 2004
7,896,852 Anti-infective central venous catheter with diffusion barrier layer 1 2005
8,089,029 Bioabsorbable metal medical device and method of manufacture 1 2006
8,187,620 Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents 1 2006
8,048,150 Endoprosthesis having a fiber meshwork disposed thereon 1 2006
7,947,031 Anti-infective central venous catheter with diffusion barrier layer 0 2006
8,067,054 Stents with ceramic drug reservoir layer and methods of making and using the same 2 2007
7,976,915 Endoprosthesis with select ceramic morphology 1 2007
8,771,343 Medical devices with selective titanium oxide coatings 0 2007
8,002,823 Endoprosthesis coating 1 2007
7,942,926 Endoprosthesis coating 1 2007
7,931,683 Articles having ceramic coated surfaces 13 2007
8,052,743 Endoprosthesis with three-dimensional disintegration control 0 2007
8,353,949 Medical devices with drug-eluting coating 1 2007
8,052,744 Medical devices and methods of making the same 2 2007
8,052,745 Endoprosthesis 0 2007
8,002,821 Bioerodible metallic ENDOPROSTHESES 3 2007
8,128,689 Bioerodible endoprosthesis with biostable inorganic layers 1 2007
8,057,534 Bioerodible endoprostheses and methods of making the same 6 2007
7,981,150 Endoprosthesis with coatings 5 2007
8,216,632 Endoprosthesis coating 0 2007
8,029,554 Stent with embedded material 3 2007
7,938,855 Deformable underlayer for stent 2 2007
8,080,055 Bioerodible endoprostheses and methods of making the same 0 2007
8,431,149 Coated medical devices for abluminal drug delivery 0 2008
8,070,797 Medical device with a porous surface for delivery of a therapeutic agent 3 2008
7,998,192 Endoprostheses 1 2008
8,236,046 Bioerodible endoprosthesis 0 2008
8,221,822 Medical device coating by laser cladding 0 2008
7,985,252 Bioerodible endoprosthesis 2 2008
8,382,824 Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides 0 2008
8,071,156 Endoprostheses 1 2009
8,287,937 Endoprosthese 1 2009
8,449,603 Endoprosthesis coating 1 2009
8,231,980 Medical implants including iridium oxide 0 2009
8,267,992 Self-buffering medical implants 0 2010
8,066,763 Drug-releasing stent with ceramic-containing layer 0 2010
8,574,615 Medical devices having nanoporous coatings for controlled therapeutic agent delivery 0 2010
8,668,732 Surface treated bioerodible metal endoprostheses 0 2011
8,669,360 Methods of converting amorphous drug substance into crystalline form 0 2011
8,715,339 Bioerodible endoprostheses and methods of making the same 0 2011
 
CARDIO FLOW, INC. (7)
8,142,458 Rotational atherectomy device with fluid inflatable support elements and torque transmitting membrane 1 2007
8,137,369 Rotational atherectomy device with fluid inflatable support elements supported by fluid bearings 1 2007
8,388,637 Rotational atherectomy device with fluid inflatable support elements and distal protection capability 1 2012
8,500,764 Rotational atherectomy device with fluid inflatable support elements supported by fluid bearings 1 2012
8,496,678 Rotational device with inflatable support elements and torque transmitting membrane 1 2012
8,454,638 Atherectomy device supported by fluid bearings 1 2012
8,663,195 Rotational atherectomy device with fluid inflatable support elements and distal protection capability 0 2013
 
KIMBERLY-CLARK WORLDWIDE, INC. (3)
7,780,638 Catheter for uniform delivery of medication 1 2000
7,510,550 Catheter for uniform delivery of medication 2 2003
8,048,057 Catheter for uniform delivery of medication 0 2009
 
INSULINE MEDICAL LTD. (2)
8,622,991 Method and device for drug delivery 0 2008
8,409,133 Drug delivery device with sensor for closed-loop operation 0 2008
 
Lela Nadirashvili (2)
8,157,825 Atherectomy device supported by fluid bearings 1 2007
8,109,955 Rotational atherectomy device with fluid inflatable support elements and distal protection capability 1 2007
 
ACTIVEIN LTD. (1)
7,749,193 Vascular coupling device 0 2003
 
HEMOTEQ AG (1)
8,597,720 Medical product for treating stenosis of body passages and for preventing threatening restenosis 0 2008
 
INTERFACE ASSOCIATES, INC. (1)
8,568,648 Methods for manufacturing multi-layer balloons for medical applications 0 2011
 
Lela Nadirashvilli (1)
8,147,507 Rotational atherectomy device with fluid inflatable support elements and two torque transmitting coils 0 2007
 
NOVOSTE CORPORATION (1)
7,108,684 Drug delivery balloon catheter 18 2003
 
REMON MEDICAL TECHNOLOGIES LTD. (1)
8,303,643 Method and device for electrochemical formation of therapeutic species in vivo 0 2010
 
ZIMMER SPINE, INC. (1)
8,382,840 Spinal implant delivery methods and devices 0 2009

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Apr 18, 2017
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00

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