Ti-3 protein derived from triatoma infestans exhibiting activity to inhibit platelet aggregation
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United States of America Patent
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Oct 18, 2005
Grant Date -
Apr 15, 2004
app pub date -
Mar 28, 2003
filing date -
Oct 2, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides Ti-3 protein, which is a protein obtained from salivary gland of Triatoma infestans, and the present invention provides Ti-3 gene encoding the protein. As the Ti-3 protein exhibits inhibitory activity on platelet aggregation, a medicine comprising the Ti-3 protein as an active ingredient will serve as a platelet aggregation inhibitor possibly effective for prevention and treatment of myocardial infarction, pulmonary infarction and cerebral infarction. Moreover, the Ti-3 protein will also serve as a highly prospective lead compound in the development of novel platelet aggregation inhibitors.
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