4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein
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United States of America Patent
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Oct 25, 2005
Grant Date -
May 23, 2002
app pub date -
Oct 31, 2001
filing date -
Sep 18, 1997
priority date (Note) -
Expired
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Abstract
Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.
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