Hybrid polyketide synthases combining heterologous loading and extender modules
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United States of America Patent
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Nov 1, 2005
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app pub date -
Oct 25, 1999
filing date -
Jul 5, 1996
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Abstract
A hybrid type I polyketide synthase gene typically containing a starter module and a plurality of heterologous extender modules is used to synthesize novel polyketides. It is preferably under the control of a type II polypolyketide synthase promoter e.g. act I of S. coelicolor.
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