Process for the synthesis of pyrazolopyrimidines
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United States of America Patent
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Nov 8, 2005
Grant Date -
Apr 24, 2003
app pub date -
Sep 12, 2001
filing date -
Sep 12, 2001
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Abstract
The present invention provides a nucleoside comprising a pyrazolopyrimidine base and a process for producing the same. In particular, the processes of the present invention comprises using a halogenated pyrazolopyrimidine base and removing the halogen after the base is coupled to a sugar moiety. The presence of the halogen on the nucleoside base allows facile and economical production of a large quantity of nucleosides.
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