Pravastatin pharmaceutical formulations and methods of their use
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United States of America Patent
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Nov 22, 2005
Grant Date -
Sep 18, 2003
app pub date -
Jan 10, 2003
filing date -
Jan 11, 2002
priority date (Note) -
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Abstract
The present invention relates to formulations comprising a therapeutically effective amount of pravastatin, or a pharmaceutically acceptable salt thereof, and methods of their use. The present formulations and methods are designed to release little or no pravastatin in the stomach but release a therapeutic amount of pravastatin in the small intestine, thereby limiting systemic exposure of the body to pravastatin and maximizing hepatic-specific absorption of the drug. The formulations and methods of the present invention are particularly useful for treating and/or preventing conditions that are benefited by decreasing levels of lipids and/or cholesterol in the body.
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