Optically active carbonates as precursors of (+)-zopiclone
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United States of America Patent
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Nov 29, 2005
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N/A
app pub date -
Apr 2, 2003
filing date -
Apr 3, 2002
priority date (Note) -
Expired
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Abstract
In the present invention new compounds of formula II, in enantiomerically enriched forms, are described for the first time, where R1 is chloroalkyl. The present invention also includes several new enzymatic processes for the resolution of the enantiomers of the aforementioned carbonates of formula II from the corresponding racemic mixture. The transformation of these carbonates into zopiclone enantiomerically enriched, constitutes an additional aspect of the invention.
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