Small triplex forming PNA oligos
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United States of America Patent
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Dec 27, 2005
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app pub date -
Aug 21, 1998
filing date -
Aug 22, 1997
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Abstract
A method for the determination of nucleic acids which is highly specific and simple comprises the formation of a triple stranded binding complex including two separate, different probe molecules and detecting the formation of the complex via the inclusion of one of the probes. The method can be used to differentiate between nucleic acids having a single base difference in sequence.
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