Systems for applying cross-linked mechanical barriers
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United States of America Patent
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-
Feb 7, 2006
Grant Date -
Oct 18, 2001
app pub date -
Feb 28, 2001
filing date -
Aug 26, 1998
priority date (Note) -
In Force
status (Latency Note)
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Abstract
A delivery device applies a biocompatible and biodegradable barrier material to a tissue region, e.g., to seal a vascular puncture site. The material comprises two liquid components, which are pre-packaged in individual dispensers. Upon mixing, the liquid components cross-link to create a barrier matrix. A holder attaches to the delivery device. The holder mutually supports the first and second dispensers while the protein solution and polymer solution are conveyed from the dispensers into a fluid delivery channel. The protein and polymer solutions mix as a result of flow through the channel.
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