Antibodies that recognize and bind phosphorylated human glucocorticoid receptor and methods of using same
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United States of America Patent
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Feb 7, 2006
Grant Date -
Dec 9, 2004
app pub date -
Jul 30, 2003
filing date -
Aug 13, 2002
priority date (Note) -
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Abstract
A molecule containing the antigen binding portion of an antibody specific for human glucocorticoid receptor phosphorylated at residue Ser211, Ser226 or Ser203 is obtained and a method of determining the presence of activated glucocorticoid receptors in cells from human glucocorticoid responsive tissue and a method of screening for a glucocorticoid agonist using the molecule, which is preferably an antibody, are provided in the present invention.
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