Nucleic acid molecules encoding modified polyketide synthases containing polylinkers and uses thereof

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United States of America Patent

PATENT NO 7001747
SERIAL NO

09743162

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Abstract

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Nucleic acid molecules encoding at least part of a Type I polyketide synthase, and having a polylinker with multiple restriction enzyme sites in place of one or more PKS genes encoding enzymes associated with reduction, optionally further including nucleic acid incorporated into the polylinker, the further nucleic acid encoding one or more reductive enzymes; plasmids incorporating such nucleic acids; host cells transfected with such plasmids; methods relating thereto.

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Patent Owner(s)

Patent OwnerAddress
BIOTICA TECHNOLOGY LIMITEDCHESTERFORD RESEARCH PARK LITTLE CHESTERFORD NR SAFFRON WALDEN ESSEX CB10 1XL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kellenberger, Johannes Basel, CH 1 2
Leadlay, Peter Francis Cambridge, GB 17 94
McArthur, Hamish Alastair Irvine Mystic, CT 8 50
Staunton, James Cambridge, GB 15 95
Stutzman-Engwall, Kim Jonelle East Lyme, CT 1 2

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