Method of inhibiting overactivity of phagocytes or lymphocytes in an individual
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United States of America Patent
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Mar 7, 2006
Grant Date -
May 29, 2003
app pub date -
Nov 26, 2001
filing date -
Nov 26, 2001
priority date (Note) -
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Abstract
The invention relates to a method of inhibiting myeloperoxidase activity in neutrophils in an individual by administering to the individual an effective amount of a lignan, where said lignan is enterolactone. The invention is further directed to a method inhibiting myeloperoxidase activity or oxidative burst of macrophages in an individual by administering to the individual an effective amount of a lignan where said lignan is enterolactone or hydroxymatairesinol or a mixture. Finally, the invention is directed to a method of inhibiting oxidative burst or myeloperoxidase activity in neutrophils in an individual by administering to the individual an effective amount of a lignan which is hydroxymatairesinol.
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