Pralmorelin-containing nasal drop preparations
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United States of America Patent
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Mar 7, 2006
Grant Date -
Jul 24, 2003
app pub date -
May 29, 2001
filing date -
May 29, 2000
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The preparation for intranasal administration comprising D-alanyl-3-(naphthalen-2-yl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide (pralmorelin) and/or an acid addition salt thereof as an active ingredient and water permits a marked increase in the in vivo absorption of pralmorelin and hence provides adequate efficacy even if it is administered in a small dose at a time. The preparation also allows pralmorelin to be dissolved in an increased amount, so it can be formulated pharmaceutically with great ease. It also high stability over time.
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