Delivery of rizatriptan or zolmitriptan through an inhalation route

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United States of America Patent

PATENT NO 7011819
SERIAL NO

10792096

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to the delivery of headache and anti-migraine compounds through an inhalation route. Specifically, it relates to aerosols containing that are used in inhalation therapy. In a method aspect of the present invention, rizatriptan or zolmitriptan is administered to a patient through an inhalation route. The method comprises: a) heating a composition, comprising rizatriptan or zolmitriptan to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol with less than 5% of the drug degradation products. In a kit aspect of the present invention, a kit for delivering rizatriptan or zolmitriptan through an inhalation route is provided which comprises: a) a thin coating of a rizatriptan or zolmitriptan composition; and, b) a device for dispending said thin coating as a condensation aerosol.

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Patent Owner(s)

Patent OwnerAddress
ALEXZA PHARMACEUTICALS INC2091 STIERLIN CT MOUNTAIN VIEW CA 94043

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hale, Ron L Woodside, CA 72 5378
Rabinowitz, Joshua D Mountain View, CA 167 12353
Solas, Dennis W San Francisco, CA 67 8017
Zaffaroni, Alejandro C Atherton, CA 109 9857

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