Oral capsule formulation with increased physical stability
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United States of America Patent
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Mar 14, 2006
Issued Date -
N/A
app pub date -
Dec 20, 2002
filing date -
Dec 21, 2001
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Abstract
A formulation for a stabilized capsule for oral administration of a hydrophobic pharmaceutically active agent; comprising a non-aqueous solubilizer selected from 2-pyrrolidone, N-alkylpyrrolidones and combinations thereof; and a capsule stabilizing agent selected from mono-, di- and triglycerides, mono- and di-fatty esters of polyethylene glycol, fatty acids and combinations thereof wherein capsule integrity is maintained for at least 24 hours is disclosed.
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