Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
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United States of America Patent
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Mar 21, 2006
Grant Date -
May 27, 2004
app pub date -
Nov 21, 2002
filing date -
Nov 21, 2002
priority date (Note) -
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status (Latency Note)
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Abstract
An implantable osmotically driven delivery system having a dynamic, two-way valve and a self-adjusting, variable geometry fluid flow channel. As pressure within the agent delivery system increases, the fluid channel narrows, thereby restricting flow. At exceptionally high pressures, the valve can be designed to close altogether at the orifice or delivery end, or it can provide a minimal leak path so that a maximum fluid flow is never exceeded. At zero or very low pressures, the valve will close completely at the beneficial agent reservoir end, isolating the beneficial agent formulation from external fluid infiltration and thereby eliminating diffusion of external fluid into the beneficial agent formulation.
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