Photodynamic treatment of targeted cells
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United States of America Patent
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Mar 28, 2006
Issued Date -
N/A
app pub date -
Mar 16, 2004
filing date -
Jan 15, 1999
priority date (Note) -
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Abstract
The present invention is drawn to methods for photodynamic therapy (PDT) of a target cell, target tissue or target composition in a mammalian subject, using a therapeutically effective amount of a targeted substance, which is either a targeted photosensitizing agent, or a photosensitizing agent delivery system, or a targeted prodrug. This targeted substance preferably selectively binds to the target cell, target tissue or target composition. Light at a wavelength or waveband corresponding to that which is absorbed by the targeted substance is then administered. The light intensity is relatively low, but a high total fluence is employed to ensure the activation of the targeted photosensitizing agent or targeted prodrug product.
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