Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties

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United States of America Patent

PATENT NO 7018645
SERIAL NO

09559799

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Abstract

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A water soluble, biodegradable reverse thermal gelation system comprising a mixture of at least two types of tri-block copolymer components is disclosed. The tri-block copolymer components are made of a hydrophobic biodegradable polyester A-polymer block and a hydrophilic polyethylene glycol B-polymer block. The drug release and gel matrix erosion rates of the biodegradable reverse thermal gelation system may be modulated by various parameters such as the hydrophobic/hydrophilic component contents, polymer block concentrations, molecular weights and gelation temperatures, and weight ratios of the tri-block copolymer components in the mixture.

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Patent Owner(s)

  • BTG INTERNATIONAL INC.;BTG INTERNATIONAL LIMITED

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Piao, Ai-Zhi Salt Lake City, UT 10 388
Shih, Chung Sandy, UT 33 1241

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