Powdery inhalational preparations and process for producing the same

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United States of America Patent

PATENT NO 7022311
SERIAL NO

10110340

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Abstract

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The present invention is aimed at providing a dry powder inhalation with minimal adhesive-agglomerative property during storage and with a good inhalation behavior for a pharmaceutically active ingredient, and is a dry powder inhalation wherein at least an active ingredient is adhered to the surface of a carrier particle comprised of erythritol and/or trehalose. It is also a dry powder inhalation wherein at least S-36496 and/or Pralmorelin dihydrochloride is adhered to the surface of the carrier particle. It is further a dry powder inhalation wherein at least an active ingredient and a surface modifier are adhered to the surface of the carrier particle. It is also a preparation method of these. Said dry powder inhalation may be applied to the capsules for use in an inhaler device. In addition to the achievement of above objectives, the present invention provides a dry powder inhalation with improved taste in inhalation or with reduced discomfort in the oral cavity and the throat, and a preparation method for enabling an easy preparation thereof without complicated processes.

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Patent Owner(s)

Patent OwnerAddress
KAKEN PHARMACEUTICAL CO LTDTOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kato, Yasutomi Shizuoka, JP 2 20
Kawashima, Yoshiaki Gifu, JP 10 87
Matsumoto, Keiko Shizuoka, JP 38 457
Ohkuma, Moriyuki Shizuoka, JP 1 12
Okuda, Otomo Shizuoka, JP 1 12

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