Controlled release of anti-arrhythmic agents

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7022343
APP PUB NO 20020150622A1
SERIAL NO

10033274

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Methods for the simple, reliable application and local controlled release of selected anti-arrhythmia drugs from a hydrogel applied to or polymerized on the tissues of the heart or its vessels, especially in conjunction with cardiac bypass or other cardiac surgery, have been developed. The anti-arrhythmia drugs are incorporated into hydrogels that biodegrade and adhere to the tissues to which the anti-arrhythmic drugs are to be delivered. The hydrogels may be formed in vitro or in vivo. In a preferred embodiment, the drugs are effective to lengthen atrial effective refractory period. A particularly preferred drug is amiodarone.

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Patent Owner(s)

Patent OwnerAddress
GENZYME CORPORATION450 WATER STREET CAMBRIDGE MA 02141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burns, James W Watertown, MA 22 1179
Miller, Robert J Quincy, MA 195 7847
Philbrook, C Michael Boston, MA 17 912
Skinner, Kevin C Andover, MA 2 69

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