Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
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United States of America Patent
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Apr 18, 2006
Grant Date -
Jan 29, 2004
app pub date -
Mar 5, 2003
filing date -
Sep 7, 2001
priority date (Note) -
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Abstract
Pharmaceutical compositions that include a drug and/or drug-oligomer conjugate, a fatty acid component and a bile salt component, or a bile salt component without a fatty acid component are described. The drug can be covalently coupled to an oligomeric moiety. The fatty acid component and the bile salt component, when together, can be present in a weight-to-weight ratio of between 1:15 and 15:1 or any value between. Methods of treating diseases in a subject in need of such treatment using the pharmaceutical compositions of this invention are also provided, as well as methods of providing such pharmaceutical compositions.
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