Multiple stimulus reversible hydrogels
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United States of America Patent
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Apr 25, 2006
Grant Date -
May 20, 2004
app pub date -
Nov 3, 2003
filing date -
Jun 23, 2000
priority date (Note) -
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Abstract
A polymeric solution capable of gelling upon exposure to a critical minimum value of a plurality of environmental stimuli is disclosed. The polymeric solution may be an aqueous solution utilized in vivo and capable of having the gelation reversed if at least one of the stimuli fall below, or outside the range of, the critical minimum value. The aqueous polymeric solution can be used either in industrial or pharmaceutical environments. In the medical environment, the aqueous polymeric solution is provided with either a chemical or radioisotopic therapeutic agent for delivery to a specific body part. The primary advantage of the process is that exposure to one environmental stimuli alone will not cause gelation, thereby enabling the therapeutic agent to be conducted through the body for relatively long distances without gelation occurring.
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Patent Owner(s)
| Patent Owner | Address | |
|---|---|---|
| BATTELLE MEMORIAL INSTITUTE | PACIFIC NORTHWEST NATIONAL LABORATORIES KL-53 P O BOX 999 RICHLAND WA 99352 |
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Inventor(s)
| Inventor Name | Address | # of filed Patents | Total Citations |
|---|---|---|---|
| Gutowska, Anna | Richland, WA | 14 | 482 |
| Krzyminski, Karol J | Poland, PL | 2 | 95 |
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| Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
| Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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