Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
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United States of America Patent
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Apr 25, 2006
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app pub date -
Jan 18, 2002
filing date -
Nov 19, 1996
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Abstract
Disclosed are invasive and non-invasive central nervous system (CNS) drug delivery methods and devices for use in these methods that essentially circumvent the blood-brain barrier. More specifically, the disclosed methods and devices utilize iontophoresis as delivery technique that allows for enhanced delivery of a biologically active agent into the CNS of a mammal as well as for (pre)-programmable and controlled transport.
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