Method for sequential support-bound synthesis of conjugated oligomeric compounds
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United States of America Patent
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May 2, 2006
Grant Date -
Jan 8, 2004
app pub date -
Jun 20, 2002
filing date -
Jun 20, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A sequential support-bound synthesis method is disclosed for preparing a conjugated oligomeric compound, preferably a PNA-peptide conjugate or an oligonucleotide-peptide conjugate, using a bridging molecule having at least two N-protecting amino groups. A conjugated oligomeric compound for therapeutic or prophylactic delivery is also disclosed.
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