Fusion proteins incorporating lysozyme

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United States of America Patent

PATENT NO 7045677
APP PUB NO 20030167477A1
SERIAL NO

10024597

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Abstract

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A process for the production of a peptide is disclosed, the process comprising expressing in the milk of a transgenic, non-human, placental mammal a fusion protein which comprises the peptide to be expressed linked to a fusion partner protein which is lysozyme. The fusion protein may be separate from the milk and cleaved to yield the target peptide. A transgenic, non-human, placental mammal whose genome incorporates a DNA molecule comprising a coding sequence encoding lysozyme coupled to a peptide is also described.

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Patent Owner(s)

Patent OwnerAddress
PHARMING INTELLECTUAL PROPERTY BVP O BOX 451 AL LEIDEN 2300

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cottingham, Ian Robert Edinburgh, GB 5 14
McCreath, Graham Edward Edinburgh, GB 2 10

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