Hemoglobin mutants with increased soluble expression and/or reduced nitric oxide scavenging

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7049406
APP PUB NO 20030017537A1
SERIAL NO

10107871

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Abstract

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The invention relates to novel recombinant hemoglobins having reduced nitric oxide scavenging and/or increased high soluble expression. The invention further relates to methods of increasing the soluble expression of recombinant hemoglobin by adding exogenous hemin in molar excess of the heme binding sites of recombinant hemoglobin.

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Patent Owner(s)

Patent OwnerAddress
BAXTER BIOTECH TECHNOLOGY SARLROUTE DE PIERRE-A-BOT 111 CH 2000 NEUCHATEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Doherty, Daniel H Boulder, CO 37 695
Glascock, Christopher B Louisville, CO 4 215
Lemon, Douglas D Louisville, CO 4 215
Mathews, Antony J Houston, TX 10 264
Olson, John S Houston, TX 15 171
Weickert, Michael J Belmont, CA 6 291

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