Circularly permuted fluorescent protein indicators
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United States of America Patent
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Jun 13, 2006
Grant Date -
Oct 24, 2002
app pub date -
Oct 23, 2001
filing date -
May 21, 1999
priority date (Note) -
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Abstract
Polynucleotides encoding fluorescent indicators, which contain a sensor polypeptide inserted within a fluorescent moiety, are provided, as are polypeptides encoded by such polynucleotides. Also provided are circularly permuted fluorescent polypeptides and polynucleotides encoding the circularly permuted fluorescent polypeptides. In addition, methods of using the fluorescent indicators and the circularly permuted fluorescent polypeptides are provided.
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