Yeast-based process for production of l-pac

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United States of America Patent

PATENT NO 7063969
APP PUB NO 20030077769A1
SERIAL NO

10149821

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either (a) a supereritical fluid or (b) a liquefied gas, and recovering the carbinol compound. Preferably the yeast is Saccharomyces cerevisiae. In a particularly preferred embodiment the aromatic aldehyde is benzaldehyde and the carbinol is phenylacetylcarbinol, according to the reaction (I): in which the benzaldehyde, the pyruvic acid, or both may optionally be substituted.

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Patent Owner(s)

Patent OwnerAddress
VICTORIA UNIVERSITYPO BOX 14428 FOOTSCRAY PARK CAMPUS MELBOURNE VIC 8001 AUSTRALIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Smallridge, Andrew John Elwood, AU 4 22
Trewhella, Maurice Arthur Victoria, AU 4 22
Wilkinson, Kylie Anne Victoria, AU 2 21

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