Substituted pyridinones
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United States of America Patent
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Jun 27, 2006
Grant Date -
Mar 25, 2004
app pub date -
Feb 14, 2003
filing date -
Feb 14, 2002
priority date (Note) -
In Force
status (Latency Note)
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Abstract
Disclosed are compounds Formula I ##STR00001## and pharmaceutically acceptable salts thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, and R.sub.5 are defined herein. These compounds are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical compositions containing the compounds, methods of preparing the compounds and methods of treatment using the compounds are also disclosed.
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