Polypeptides having a triggering NK activity and biological applications

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United States of America Patent

PATENT NO 7074409
APP PUB NO 20040115738A1
SERIAL NO

10451843

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Abstract

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The invention relates to polypeptides having a triggering NK activity and an aminoacid sequence that is at least 80% identical over its entire length to the polypeptide having SEQID N.degree.1, and any immunogenic fragments thereof, as well as to the polyclonal and monoclonal antibodies directed against said polypeptides, and immuno-reactive fragments thereof. Application for detecting NK cells in a sample, for their removal from a sample or for enrichment of NK cells, and for NK cell natural cytotoxicity regulation.

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Patent Owner(s)

Patent OwnerAddress
INNATE PHARMA13009 MARSEILLE
UNIVERSITA DI GENOVAVIA L B ALBERTI 2 GENOVA 16132

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Biassoni, Roberto Genoa, IT 9 17
Bottino, Cristina Genoa, IT 8 17
Moretta, Alessandro Genoa, IT 32 304

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