Opioid formulations
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United States of America Patent
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Jul 11, 2006
Grant Date -
Nov 13, 2003
app pub date -
Mar 2, 2001
filing date -
Mar 2, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides high-concentration formulations of opioids such as fentanyl or fentanyl congeners. The formulation of the invention comprises fentanyl or a fentanyl congener in concentrations significantly in excess of conventional formulations, e.g., on the order about 2-fold to about 10,000-fold greater than conventional formulations, e.g., currently commercially available formulations. These formulations are particularly useful for long-term delivery to a subject suffering from pain. The invention further provides drug delivery devices comprising the high-concentration opioid formulations, and further provides methods of alleviating pain in a subject, comprising administering the high-concentration formulations to a subject in need thereof.
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