Amidino derivatives and their use as thrombin inhibitors
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United States of America Patent
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Jul 11, 2006
Grant Date -
Apr 4, 2002
app pub date -
Apr 23, 2001
filing date -
Jul 4, 1996
priority date (Note) -
Expired
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Abstract
There is provided compounds of formula I, ##STR00001## wherein R.sup.1, R.sup.2, R.sup.3, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.
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