Human antipneumococcal antibodies from non-human animals
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United States of America Patent
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Jul 18, 2006
Grant Date -
Jan 20, 2005
app pub date -
Nov 14, 2003
filing date -
May 16, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention described herein provides human antibodies produced in non-human animals that specifically bind to Streptococcus pneumoniae capsular polysaccharide (PPS-3). The invention further provides methods for making the antibodies in a non-human animal and for expressing the antibodies in cells including hybridomas and recombinant host cell systems. Kits and pharmaceutical compositions comprising the antibodies are also provided in addition to methods of treating, inhibitng or preventing S. pneumoniae infection or conditions or disorders caused by such infection by administering to a patient the pharmaceutical compositions described herein.
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