Importance

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Abstract

A compound having the general formula (I): ##STR00001## wherein: X is N or C; R.sub.0 is H, a lower alkyl group, a lower O-alkyl group, ##STR00002## lower alkyl group, a benzyl group, a phenyl group, a heterocyclic amine group, a cycloalkyl group, a cycloalkyl group substituted with O-alkyl or, a furyl group; R.sub.1 and R.sub.2 are, independently, H, an amine group, a lower alkyl group, a lower O-alkyl group, a lower S-alkyl group or a lower N-alkyl group, or R.sub.1 and R.sub.2 taken together with the carbon atoms to which they are attached form a five-membered carbocyclic or heterocyclic ring, where the heteroatoms of the heterocyclic ring are one or two oxygen atoms, and/or where any substituent on said carbocyclic or heterocyclic ring is chosen from O, S and N; n is 0,1,2,3 or 4; m is 0 or 1; and pharmaceutically acceptable salts thereof; with the proviso that said compound is not 1-[(4-methoxyphenyl)sulfonyl]piperazine or 1-(1,3-benzodioxol-5-ylsulfonyl)piperazine. The compounds are useful as active ingredients in pharmaceutical compositions and as a medicament for the treatment of erectile dysfunction.

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First Claim