Specific inhibitors of NFAT activation by calcineurin and their use in treating immune-related diseases

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7084241
APP PUB NO 20020132300A1
SERIAL NO

10066151

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Isolated peptide fragments of the conserved regulatory domain of NFAT protein capable of inhibiting protein--protein interaction between calcineurin and NFAT, or a biologically active analog thereof are described. Isolated polynucleotides and gene therapy vectors encoding such peptide fragments are also described. In addition, methods for treating immune-related diseases or conditions and methods for high throughput screening of candidate agents are described. Pharmaceutical compositions are also provided.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
THE CBR INSITUTE FOR BIOMEDICAL RESEARCH INC800 HUNTINGTON AVE BOSTON MA 02115

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Aramburu, Jose Boston, MA 4 22
Hogan, Patrick G Cambridge, MA 8 56
Rao, Anjana Cambridge, MA 75 871

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation