Heterodimers of retinoid X receptors (RXRS) and other steroid hormone receptors
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United States of America Patent
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Aug 29, 2006
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N/A
app pub date -
Dec 24, 1991
filing date -
Dec 24, 1991
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Expired
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Abstract
This invention provides a purified heterodimer comprising an RXR and a hormone receptor. The invention also provides a method of screening ligands for their effect on the activity of an RXR-containing hormone receptor heterodimer comprising combining the heterodimer with the ligand and determining the effect on activity. Also provided is a method of amplifying the activity of a hormone receptor comprising forming a heterodimer with another hormone receptor.
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