Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-YL)methyl]-4H-carb-azol-4-one

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United States of America Patent

PATENT NO 7098345
APP PUB NO 20050020655A1
SERIAL NO

10425450

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Abstract

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A process for preparing ondansetron by transamination of an ondansetron structural analog that can be readily prepared conveniently by a Mannich reaction is provided. The process represents an improvement upon known procedures for making ondansetron by transamination because of its rapid rate, selectivity and the ease with which the product can be isolated from the reaction mixture.

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Patent Owner(s)

  • TEVA GYOGYSZERGYAR RESZVENYTARSASAG;TEVA PHARMACEUTICALS USA, INC.;TEVA GYÓGYSZERGYÁR ZÁRKÖRÜEN MÜKÖDÖ RÉSZVÉNYTÁRSASÁG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Meszaros, Sos Erzsebet Debrecen, HU 7 7
Molnar, Sandor Debrecen, HU 17 21
Salyi, Szabolcs Debrecen, HU 8 11
Szabo, Csaba Debrecen, HU 116 564
Tamas, Tivadar Debrecen, HU 23 14

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