Anti-idiotypic anti-TNF antibodies and related immunoassay methods

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United States of America Patent

PATENT NO 7101674
SERIAL NO

09897724

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Anti-TNF antibodies and anti-TNF peptides, specific for tumor necrosis factor (TNF) are useful for in vivo diagnosis and therapy of a number of TNF-mediated pathologies and conditions, as well as polynucleotides coding for anti-TNF murine and chimeric antibodies, peptides, methods of making and using the antibody or peptides in immunoassays and immuno-therapeutic approaches are provided, where the anti-TNF peptide is selected from a soluble portion of TNF receptor, an anti-TNF antibody or structural analog thereof.

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Patent Owner(s)

  • CENTOCOR, INC.;NEW YORK UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daddona, Peter Palo Alto, CA 59 1771
Ghrayeb, John Thorndale, PA 68 2681
Knight, David M Berwyn, PA 72 2518
Le, Junming Jackson Heights, NY 59 2436
Siegel, Scott A Westborough, MA 16 912
Vilcek, Jan New York, NY 54 2057

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