Apparatus and method for reversal of myocardial remodeling with electrical stimulation

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7103410
APP PUB NO 20040049236A1
SERIAL NO

10649468

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddressTotal Patents
Cardiac Pacemakers, Inc.ST PAUL, MN3060

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
KenKnight, Bruce H Maple Grove, MN 175 9189
Kramer, Andrew P Stillwater, MN 233 9071
Salo, Rodney W Fridley, MN 117 7240
Spinelli, Julio C Shoreview, MN 162 7955

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (3)
4554922 Method of inhibiting cardiac arrhythmias 143 1982
5174289 Pacing systems and methods for control of the ventricular activation sequence 249 1990
5267560 Methods for control of the ventricular activation sequence 199 1992
 
Intermedics, Inc. (3)
4880005 Pacemaker for detecting and terminating a tachycardia 323 1988
4872459 Pacemaker for detecting and terminating a tachycardia 99 1988
5792203 Universal programmable cardiac stimulation device 172 1997
 
MARDIL, INC. (1)
2002/0082,647 Cardiac disease treatment and device 76 2000
 
Ceske vysoke uceni technicke (1)
5058605 Method and device for the controlled local, non-invasive application of DC pulses to human and animal tissues 118 1990
 
IMPULSE DYNAMICS N.V. (2)
* 6317631 Controlling heart performance using a non-excitatory electric field 115 1998
6363279 Electrical muscle controller 142 2000
 
Mirowski; Mieczyslaw (1)
4928688 Method and apparatus for treating hemodynamic disfunction 465 1989
 
PFIZER INC. (1)
2002/0115,081 Diagnosis and treatment of cardiovascular conditions 35 2001
 
MEDTRONIC, INC. (11)
5014698 Method of and system for monitoring and treating a malfunctioning heart 189 1989
5233985 Cardiac pacemaker with operational amplifier output circuit 163 1991
5156149 Sensor for detecting cardiac depolarizations particularly adapted for use in a cardiac pacemaker 159 1992
5370665 Medical stimulator with multiple operational amplifier output stimulation circuits 199 1993
* 5507782 Method and apparatus for dual chamber cardiac pacing 125 1994
5683429 Method and apparatus for cardiac pacing to prevent atrial fibrillation 204 1996
5797970 System, adaptor and method to provide medical electrical stimulation 182 1996
5824019 Pacing system with physiologically timed ventricular pacing 48 1996
5851226 Temporary transvenous endocardial lead 83 1996
6223082 Four-chamber pacing system for optimizing cardic output and determining heart condition 135 2000
* 6507756 Dual chamber pacing system having time-adaptive AV delay 102 2000
 
Biosense, Inc. (1)
6066094 Cardiac electromechanics 140 1998
 
AKAMAI TECHNOLOGIES, INC. (1)
* 2009/0132,648 CONTENT DELIVERY AND GLOBAL TRAFFIC MANAGEMENT NETWORK SYSTEM 89 2009
 
EV Vascular, Inc. (1)
6556872 Therapeutic device and method for treating diseases of cardiac muscle 31 2000
 
Cardiac Pacemakers, Inc. (14)
4674518 Method and apparatus for measuring ventricular volume 266 1985
5158079 Implantable device for preventing tachyarrhythmias 41 1991
5935160 Left ventricular access lead for heart failure pacing 214 1997
6112117 Method and apparatus for treating cardiac arrhythmia using electrogram features 82 1997
6152955 Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation 57 1999
6038483 Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation 42 1999
6058329 Optimization of pacing parameters based on measurement of acoustic noise 179 1999
6151524 Apparatus and method for treating ventricular tachyarrhythmias 146 1999
6418343 Method and apparatus for adjusting the sensing threshold of a cardiac rhythm management device 82 1999
* 6640135 Apparatus and method for spatially and temporally distributing cardiac electrical stimulation 36 2000
6574506 System and method for timing synchronized pacing 69 2000
6628988 Apparatus and method for reversal of myocardial remodeling with electrical stimulation 192 2001
6973349 Method and apparatus for minimizing post-infarct ventricular remodeling 67 2001
6915160 Dynamically optimized multisite cardiac resynchronization device 68 2002
 
KNISLEY, STEPHEN B. (1)
5995871 System and method for cardioversion using scan stimulation 79 1997
 
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (1)
* 6868287 Cardiac remodeling 12 2000
 
Pacesetter, Inc. (3)
4628934 Method and means of electrode selection for pacemaker with multielectrode leads 193 1984
5109842 Implantable tachyarrhythmia control system having a patch electrode with an integrated cardiac activity system 174 1990
2002/0002,389 Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart 115 2001
 
SORIN CRM SAS (3)
5514161 Methods and apparatus for controlling atrial stimulation in a double atrial triple chamber cardiac pacemaker 215 1995
5584867 Method and apparatus for controlling a double atrial triple chamber cardiac pacemaker having a fallback mode 212 1995
5995870 Multi-site cardiac stimulator for the treatment of cardiac insufficiency by stimulation 42 1998
 
VITATRON MEDICAL, B.V. (2)
4549548 Pacemaker system with automatic event-programmed switching between unipolar and bipolar operation 160 1983
5534016 Dual chamber pacing system and method utilizing detection of ventricular fusion for adjustment of the atrial-ventricular delay as therapy for hypertrophic obstructive cardiomyopathy 132 1995
 
GRAEMED PTY LIMITED (1)
5674259 Multi-focal leadless apical cardiac pacemaker 204 1995
 
ABIOMED, INC. (1)
* 6314322 System and method for treating dilated cardiomyopathy using end diastolic volume (EDV) sensing 79 1998
* Cited By Examiner

Patent Citation Ranking

Forward Cite Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (3)
* 2009/0254,141 APPARATUS AND METHOD FOR REVERSAL OF MYOCARDIAL REMODELING WITH ELECTRICAL STIMULATION 11 2009
* 2011/0071,588 CARDIAC PACING USING ADJUSTABLE ATRIO-VENTRICULAR DELAYS 3 2010
* 2012/0041,505 PRE-EXCITATION PACING FOR TREATMENT OF HYPERTENSION 1 2011
 
Cardiac Pacemakers, Inc. (32)
7292887 Apparatus and method for spatially and temporally distributing cardiac electrical stimulation 17 2003
* 2004/0030,357 Apparatus and method for spatially and temporally distributing cardiac electrical stimulation 6 2003
* 7392084 Demand-based cardiac function therapy 21 2003
7572226 System and method for monitoring autonomic balance and physical activity 13 2003
7676259 Dynamically optimized multisite cardiac resynchronization device 7 2005
* 2005/0216,066 Dynamically optimized multisite cardiac resynchronization device 18 2005
7366568 Controlled delivery of intermittent stress augmentation pacing for cardioprotective effect 24 2005
* 7548782 Method for reversal of myocardial remodeling with electrical stimulation 13 2006
* 2006/0293,716 APPARATUS AND METHOD FOR REVERSAL OF MYOCARDIAL REMODELING WITH ELECTRICAL STIMULATION 9 2006
* 8046070 Pre-excitation pacing for treatment of hypertension 6 2006
* 2008/0109,043 PRE-EXCITATION PACING FOR TREATMENT OF HYPERTENSION 22 2006
8560067 Apparatus for spatially and temporally distributing cardiac electrical stimulation 0 2007
8090442 Apparatus and method for spatially and temporally distributing cardiac electrical stimulation 1 2007
* 2008/0097,541 APPARATUS AND METHOD FOR SPATIALLY AND TEMPORALLY DISTRIBUTING CARDIAC ELECTRICAL STIMULATION 9 2007
* 2008/0097,538 APPARATUS AND METHOD FOR SPATIALLY AND TEMPORALLY DISTRIBUTING CARDIAC ELECTRICAL STIMULATION 8 2007
8027723 Controlled delivery of intermittent stress augmentation pacing for cardioprotective effect 8 2008
* 2008/0215,105 CONTROLLED DELIVERY OF INTERMITTENT STRESS AUGMENTATION PACING FOR CARDIOPROTECTIVE EFFECT 14 2008
8065003 Demand-based cardiac function therapy 3 2008
7899532 Method and apparatus for minimizing post-infarct ventricular remodeling 1 2009
* 8521278 Smart delay for intermittent stress therapy 1 2009
* 2009/0281,591 SMART DELAY FOR INTERMITTENT STRESS THERAPY 20 2009
8046066 Apparatus for reversal of myocardial remodeling with pre-excitation 3 2009
7833164 System and method for monitoring autonomic balance and physical activity 4 2009
8103345 Cardiac pacing using adjustable atrio-ventricular delays 3 2010
8612001 Method and apparatus for minimizing post-infarct ventricular remodeling 0 2011
8611998 Controlled delivery of intermittent stress augmentation pacing for cardioprotective effect 1 2011
8369948 Apparatus for reversal of myocardial remodeling with pre-excitation 1 2011
* 8295928 Pre-excitation pacing for treatment of hypertension 0 2011
8551010 Respiration monitoring for heart failure using implantable device 4 2012
* 8594791 Pre-excitation pacing for treatment of hypertension 0 2012
* 2013/0046,355 PRE-EXCITATION PACING FOR TREATMENT OF HYPERTENSION 0 2012
8634913 Apparatus for reversal of myocardial remodeling with pre-excitation 0 2013
 
BACKBEAT MEDICAL, INC. (9)
8086315 Cardiac stimulation apparatus and method for the control of hypertension 8 2008
* 2009/0018,608 CARDIAC STIMULATION APPARATUS AND METHOD FOR THE CONTROL OF HYPERTENSION 32 2008
8428729 Cardiac stimulation apparatus and method for the control of hypertension 6 2011
9008769 Methods and systems for lowering blood pressure through reduction of ventricle filling 9 2013
9320903 Cardiac stimulation apparatus and method for the control of hypertension 2 2013
9370662 Methods and systems for controlling blood pressure by controlling atrial pressure 5 2014
9333352 Methods and systems for lowering blood pressure through reduction of ventricle filling 5 2015
9526900 Methods and systems for controlling blood pressure by controlling atrial pressure 3 2015
9656086 Methods and systems for lowering blood pressure through reduction of ventricle filling 1 2016
 
MEDTRONIC, INC. (3)
8126549 Cardiac protection system and method 7 2008
8423141 Pre-excitation stimulus timing based on mechanical event 0 2009
* 2010/0198,294 PRE-EXCITATION STIMULUS TIMING BASED ON MECHANICAL EVENT 1 2009
* Cited By Examiner

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
11.5 Year Payment $7400.00 $3700.00 $1850.00 Mar 5, 2018
Fee Large entity fee small entity fee micro entity fee
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00