Immunogenic formulation and process for preparation thereof
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United States of America Patent
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Oct 10, 2006
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app pub date -
Feb 8, 2002
filing date -
Oct 9, 1998
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Abstract
A process is disclosed for preparation of a immunogenic peptide mixture in a single synthesis. The peptide mixture collectively represents the in vivo variability seen in immunogenic epitopes from a pathogen. The mixture is termed a hypervariable epitope construct (HEC). Immunization with a HEC evokes broadly reactive immunity against divergent strains of a pathogen upon which the HEC is based.
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