Methods and compositions for identifying receptor effectors
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Oct 17, 2006
Grant Date -
Oct 4, 2001
app pub date -
Dec 21, 2000
filing date -
Mar 31, 1993
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention makes available a rapid, effective assay for screening and identifying pharmaceutically effective compounds that specifically interact with and modulate the activity of a cellular receptor or ion channel. The subject assay enables rapid screening of large numbers of polypeptides in a library to identifying those polypeptides which induce or antagonize receptor bioactivity. The subject assay is particularly amenable for identifying surrogate ligands for orphan receptors.
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