US Patent No: 7,128,067

Number of patents in Portfolio can not be more than 2000

Method and apparatus for generating an aerosol

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ALSO PUBLISHED AS: 20040016427
ATTORNEY / AGENT: (SPONSORED)
 

Importance

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Abstract

An aerosol is formed by supplying a material in liquid form to a flow passage and heating the flow passage such that the material volatizes and expands out of an open end of the flow passage. The volatized material combines with ambient air such that volatized material condenses to form the aerosol. An apparatus and method for generating such an aerosol are disclosed wherein the apparatus may include an electrically conductive sleeve at an open end of the flow passage, an electrically conductive flow passage and/or a spacer chamber. The volatilized material may contain a volatilized solute and vehicle such that the resulting aerosol particle sizes of the solute and the vehicle are either different or the same.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
PHILIP MORRIS USA INC.RICHMOND, VA521

International Classification(s)

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  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Byron, Peter R Richmond, VA 12 467
Hindle, Michael Glen Allen, VA 7 129

Cited Art

Patent Info (Count) # Cites Year
 
ARADIGM CORPORATION (20)
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5,522,385 Dynamic particle size control for aerosolized drug delivery 122 1994
5,957,124 Dynamic particle size control for aerosolized drug delivery 162 1995
6,098,620 Device for aerosolizing narcotics 69 1995
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5,819,726 Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease 25 1997
6,131,567 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 43 1998
6,192,882 Formulation and devices for monitoring the efficacy of the delivery of aerosols 44 1998
6,085,753 Insulin delivery enhanced by coached breathing 37 1998
6,123,068 Systems for the intrapulmonary delivery of aerosolized aqueous formulations 45 1998
5,970,973 Method of delivering insulin lispro 50 1998
6,098,615 Method of reproducibly effecting a patient's glucose level 37 1998
6,131,570 Temperature controlling device for aerosol drug delivery 147 1998
6,070,575 Aerosol-forming porous membrane with certain pore structure 44 1998
6,288,360 Excimer laser ablation process control of multilaminate materials 31 1999
6,167,880 Inhaled insulin dosage control delivery enhanced by controlling total inhaled volume 60 1999
6,295,986 Reactive ion etching method of fabricating nozzles for aerosolized delivery of therapeutic or diagnostic agents 36 2000
6,230,706 Method and device for creating aerosol with porous membrane with certain pore structure 36 2000
6,250,298 Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin 38 2000
6,263,872 Temperature controlling device for aerosol drug delivery 61 2000
 
NOVARTIS PHARMA AG (17)
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6,258,341 Stable glassy state powder formulations 61 1996
6,231,851 Methods and compositions for the dry powder formulation of interferons 49 1997
6,187,344 Powdered pharmaceutical formulations having improved dispersibility 45 1997
6,138,668 Method and device for delivering aerosolized medicaments 58 1997
6,077,543 Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients 76 1997
6,089,228 Apparatus and methods for dispersing dry powder medicaments 62 1998
6,136,346 Powdered pharmaceutical formulations having improved dispersibility 57 1998
6,085,740 Liquid dispensing apparatus and methods 137 1998
6,080,721 Pulmonary delivery of active fragments of parathyroid hormone 34 1998
6,267,155 Powder filling systems, apparatus and methods 39 1998
6,182,712 Power filling apparatus and methods for their use 42 1998
6,103,270 Methods and system for processing dispersible fine powders 42 1999
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6,165,463 Dispersible antibody compositions and methods for their preparation and use 63 1999
6,235,177 Method for the construction of an aperture plate for dispensing liquid droplets 52 1999
6,123,936 Methods and compositions for the dry powder formulation of interferons 55 1999
 
UNIVERSIDAD DE SEVILLA (7)
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ASTRA AKTIEBOLAG (3)
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PHILIP MORRIS INCORPORATED (3)
5,060,671 Flavor generating article 177 1989
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SIEMENS AKTIENGESELLSCHAFT (3)
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BATTELLE MEMORIAL INSTITUTE (2)
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GLAXO GROUP LIMITED (2)
4,627,432 Devices for administering medicaments to patients 247 1983
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PHILIP MORRIS PRODUCTS INC. (2)
5,144,962 Flavor-delivery article 157 1989
5,730,158 Heater element of an electrical smoking article and method for making same 28 1995
 
PHILIP MORRIS USA INC. (2)
5,743,251 Aerosol and a method and apparatus for generating an aerosol 171 1996
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STAMFORD DEVICES LIMITED (2)
6,014,970 Methods and apparatus for storing chemical compounds in a portable inhaler 106 1998
6,205,999 Methods and apparatus for storing chemical compounds in a portable inhaler 61 1998
 
THE JOHNS HOPKINS UNIVERSITY (2)
4,790,305 Medication delivery system 130 1986
4,926,852 Medication delivery system phase one 141 1988
 
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A&D COMPANY, LIMITED (1)
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ABBVIE INC. (1)
5,682,874 System for connecting an inhalation agent container to a vaporizer 29 1995
 
ADVANCED INHALATIONS REVOLUTIONS, INC. (1)
6,095,153 Vaporization of volatile materials 150 1998
 
AFFYMETRIX, INC. (1)
6,284,525 Miniature reaction chamber and devices incorporating same 37 2000
 
AGILENT TECHNOLOGIES, INC. (1)
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ALFILL GETRANKETECHNIK GMBH (1)
5,125,441 Apparatus for filling bottles with a liquid 22 1991
 
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4,974,754 Metering apparatus for metering and delivering fluid or pasty substances and use of said metering apparatus 54 1988
 
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6,294,204 Method of producing morphologically uniform microcapsules and microcapsules produced by this method 46 1998
 
AMESBURY TRUST (1)
4,700,657 Fingerprinting system incorporating a spray container and a portable vapor tank 29 1985
 
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5,151,827 Self-supporting mirror and method for the manufacture thereof 22 1991
 
BAXTER INTERNATIONAL INC. (1)
4,261,356 Method and apparatus for controlling the dispensing of fluid 56 1978
 
BAYLOR COLLEGE OF MEDICINE (1)
4,649,911 Small particle aerosol generator for treatment of respiratory disease including the lungs 93 1986
 
BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (1)
5,044,565 Forming fine particles 24 1990
 
CELANESE ACETATE LLC (1)
4,744,932 Process for forming a skinless hollow fiber of a cellulose ester 48 1985
 
CIMCO, INC. (1)
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CITY OF HOPE (1)
5,230,445 Micro delivery valve 33 1991
 
CLARKE ENGINEERING TECHNOLOGIES, INC. (1)
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CLAVIUS DEVICES INC., A CORPORATION ORGANIZED UNDER THE LAWS OF THE STATE OF NEW YORK (1)
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5,978,548 Device for gasifying liquid and for metering the gas thereby obtained 24 1998
 
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ENERGY, UNITED STATES DEPARTMENT OF (1)
4,575,609 Concentric micro-nebulizer for direct sample insertion 53 1984
 
FISCHER; JUERGEN L. (1)
5,056,511 Method and apparatus for compressing, atomizing, and spraying liquid substances 38 1989
 
FLUID ENERGY CONVERSION, INC. (1)
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GEORGIA TECH RESEARCH CORPORATION (1)
4,762,995 Monodisperse aerosol generator 43 1986
 
GLAXO WELLCOME INC. (1)
6,076,522 Metering apparatus 35 1998
 
HENKEL ECOLAB GMBH & CO. OHG (1)
5,765,724 Method and a removal unit for emptying a container filled with a thixotropic paste 27 1996
 
HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (1)
6,206,242 Pot with a flexible storage barrel and follow-up plate 29 1999
 
HITACHI, LTD. (1)
5,298,744 Mass spectrometer 28 1993
 
HUDSON OXYGEN THERAPY SALES COMPANY, A CA CORP. (1)
4,512,341 Nebulizer with capillary feed 72 1982
 
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INTERNATIONAL BUSINESS MACHINES CORPORATION (1)
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IVAC MEDICAL SYSTEMS, INC. (1)
5,342,180 Pump mechanism having a drive motor with an external rotor 73 1992
 
KABUSHIKI KAISHA ALPHA GIKEN (1)
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KAZ, INC. (1)
6,164,630 Portable humidifier with water treatment substance dispenser 25 1998
 
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LOUIS GIBECK AD (1)
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MACDONALD; ANGUS COLLINGWOOD (1)
5,564,442 Battery powered nicotine vaporizer 127 1995
 
MASCO CORPORATION OF INDIANA (1)
4,395,303 Method of manufacturing thin-walled corrosion resistant metallic objects 27 1981
 
MICHALCHIK, MICHAEL, MICHALCHIK, FROUGHEIH, AS JOINT TENANTS (1)
4,776,515 Electrodynamic aerosol generator 61 1986
 
MICROCOATING TECHNOLOGIES, INC. (1)
6,276,347 Systems and methods for delivering atomized fluids 43 1998
 
MIXPAC SYSTEMS AG (1)
5,178,305 Dispensing cartridge with storage cylinder and dispensing piston having a closure sealed vent bore 41 1991
 
MMM, LTD. (1)
5,096,092 Food dispensing apparatus utilizing inflatable bladder 50 1990
 
NEKTAR THERAPEUTICS (1)
6,207,135 Gaseous microparticles for ultrasonic diagnosis and process for their production 30 1999
 
NGK SPARK PLUG CO., LTD. (1)
6,071,554 Process for forming electrode for ceramic sensor element by electroless plating 14 1998
 
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5,872,010 Microscale fluid handling system 266 1996
 
OATEY CO. (1)
4,231,492 Apparatus and method for dispensing putty-like material 52 1978
 
OMNISHELL 1300 FOUNTAIN SQUARE SOUTH, CINCINNATI, OH 45202 A CORP OF DE (1)
4,291,838 Nebulizer and associated heater 36 1979
 
RESEARCH CORPORATION (1)
4,730,111 Ion vapor source for mass spectrometry of liquids 59 1986
 
RESEARCH DEVELOPMENT FOUNDATION (1)
5,958,378 High dose liposomal aerosol formulations containing cyclosporin A or budesonide 21 1996
 
ROGERS, ROBERT L. (1)
6,159,188 Apparatus and method for delivery of micro and submicro quantities of materials 34 1998
 
SAFEWAY PRODUCTS, INC. (1)
4,682,010 In-line electric heater for an aerosol delivery system 87 1985
 
SES, INCORPORATED (1)
4,259,409 Electroless plating process for glass or ceramic bodies and product 33 1980
 
SIRCHIE FINGERPRINT LABORATORIES COMPANY (1)
4,258,073 Taking of finger prints 39 1979
 
SMITHS MEDICAL ASD, INC. (1)
4,911,157 Self-regulating, heated nebulizer system 72 1989
 
STEINER COMPANY, INC. (1)
5,421,489 Push-type soap dispenser 54 1994
 
STEINER CORPORATION (1)
4,391,308 Soap dispensing system 59 1981
 
TENAX CORPORATION (1)
5,217,004 Inhalation actuated dispensing apparatus 88 1990
 
THE AEROGEN COMPANY LIMITED (1)
6,116,893 Burner assemblies 23 1999
 
THE PROCTER & GAMBLE COMPANY (1)
4,735,217 Dosing device to provide vaporized medicament to the lungs as a fine aerosol 192 1986
 
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THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (1)
5,756,995 Ion interface for mass spectrometer 23 1997
 
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (1)
5,474,059 Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient 71 1995
 
TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (1)
4,837,260 Cyanoacrylate compositions 53 1987
 
TSI INCORPORATED (1)
6,158,431 Portable systems and methods for delivery of therapeutic material to the pulmonary system 188 1998
 
UNIVERSITY OF DELAWARE (1)
5,565,677 Aerodynamic nozzle for aerosol particle beam formation into a vacuum 38 1995
 
VITA MEDICAL AUSTRALIA PTY LIMITED (1)
5,228,444 Device for producing a gas-lite radionuclide composition 25 1991
 
VOTRAN MEDICAL TECHNOLOGY, INC., A CORP. OF CA (1)
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WELLDYNAMICS, B.V. (1)
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OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (13)
4,215,708 Cigarettepipe with purifier 55 1978
4,289,003 Key holder 23 1979
4,303,083 Device for evaporation and inhalation of volatile compounds and medications 160 1980
4,433,797 Metered quantity dispensing valve 41 1981
4,871,115 Smoke generating apparatus 36 1987
4,848,374 Smoking device 126 1988
5,133,343 Apparatus for supporting an inhaler 39 1988
5,007,419 Inhaler device 64 1989
5,349,946 Microprocessor controlled flow regulated molecular humidifier 88 1992
5,299,565 Portable nebulizer apparatus 57 1992
5,395,445 Method and apparatus for detecting fingerprints on skin 27 1993
5,617,844 Aerosol medication delivery system 112 1995
2009/0132,648 CONTENT DELIVERY AND GLOBAL TRAFFIC MANAGEMENT NETWORK SYSTEM 2009

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
PHILIP MORRIS USA INC. (2)
7,501,113 Aerosol formulations and aerosol delivery of buprenorphine 1 2003
7,410,635 Aerosol formulations and aerosol delivery of scopolamine 0 2004
 
ALEXZA PHARMACEUTICALS, INC. (1)
7,470,421 Delivery of diazepam through an inhalation route 8 2006
 
DISNEY ENTERPRISES, INC. (1)
8,422,869 Handheld low-voltage fog effects system 0 2009
 
KAER BIOTHERAPEUTICS CORPORATION (1)
7,802,569 Aerosol processing and inhalation method and system for high dose rate aerosol drug delivery 1 2005
 
MANNKIND CORPORATION (1)
8,424,518 Dry powder inhaler and system for drug delivery 0 2009

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Apr 30, 2014
11.5 Year Payment $7400.00 $3700.00 $1850.00 Apr 30, 2018
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00