Method for down-regulation of amyloid

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7135181
APP PUB NO 20020187157A1
SERIAL NO

09785215

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Abstract

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A method for in vivo down-regulation of amyloid protein in an animal, including a human being, the method comprising effecting presentation to the animal's immune system of an immunogenically effective amount of at least one amyloidogenic polypeptide or subsequence thereof which has been formulated so that immunization of the animal with the amyloidgenic polypeptide or subsequence thereof induces production of antibodies against the amyloidogenic polypeptide, and/or at least one analogue of the amyloidogenic polypeptide wherein is introduced at least one modification in the amino acid sequence of the amyloidogenic polypeptide which has as a result the immunization of the animal with the analogue induces production of antibodies against the amyloidogenic polypeptide.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
H. LUNDBECK A/SVALBY-COPENHAGEN217

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jensen, Martin Roland Holte, DK 12 112
Nielsen, Klaus Gregorius Soborg, DK 16 233
Rasmussen, Peter Birk Frederiksberg, DK 25 199

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (2)
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
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Janssen Alzheimer Immunotherapy (3)
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MUSASHI ENGINEERING KABUSHIKI KAISHA (1)
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4599230 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants 124 1984
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THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (1)
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TRUSTEES OF BOSTON UNIVERSITY (1)
5200339 Proteases causing abnormal degradation of amyloid .beta.-protein precursor 42 1991
 
SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (1)
4608251 LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues 95 1984
 
BAVARIAN NORDIC A/S (1)
2004/0141,958 Novel methods for therapeutic vaccination 41 2003
 
ALCON RESEARCH, LTD. (1)
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H. LUNDBECK A/S (2)
* 2003/0086,938 Novel methods for down-regulation of amyloid 32 2002
2003/0157,117 Novel method for down-regulation of amyloid 24 2002
 
SCIOS NOVA, Inc. (1)
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NEW YORK UNIVERSITY (1)
* 6713450 Synthetic immunogenic but non-amyloidogenic peptides homologous to amyloid .beta. for induction of an immune response to amyloid .beta. and amyloid deposits 52 2001
* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
* 2013/0287,807 COMPOUNDS FOR TREATING SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE 0 2013
 
ID BIOMEDICAL CORPORATION (1)
* 2006/0229,233 Compositions and methods for treating neurological disorders 12 2005
 
CROSSBETA BIOSCIENCES B.V. (10)
* 2006/0045,853 Cross-beta structure comprising amyloid-binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity 3 2005
* 2007/0003,552 Cross-beta structure comprising amyloid binding proteins and methods for detection of the cross-beta structure, for modulating cross-beta structures fibril formation and for modulating cross-beta structure-mediated toxicity and method for interfering with blood coagulation 8 2005
8114832 Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition 0 2005
* 2007/0015,206 Method for detecting and/or removing protien comprising a cross-beta structure from a pharmaceutical composition 4 2005
* 2009/0202,980 Cross-Beta Structure Comprising Amyloid Binding Proteins and Methods for Detection of the Cross-Beta Structure, for Modulating Cross-Beta Structures Fibril Formation and for Modulating Cross-Beta Structure-Mediated Toxicity and Method for Interfering With Blood Coagulation 3 2006
8067187 Cross-β structure binding compounds 0 2006
* 2008/0207,488 Method for Detecting Peptides Comprising a Cross-B Structure 3 2006
* 2010/0015,126 Methods of Binding of Cross-Beta Structures By Chaperones 4 2007
8158585 Cross-β structure comprising amyloid-binding proteins and methods for detection of the cross-β structure, for modulating cross-β structures fiber formation and modulating cross-β structure-mediated toxicity 0 2007
* 2009/0191,228 Immunogenic compositions capable of activating T-cells 4 2008
 
INTEZYNE TECHNOLOGIES, INC. (2)
7618944 Encapsulated amyloid-beta peptides 28 2008
* 2008/0274,965 ENCAPSULATED AMYLOID-BETA PEPTIDES 5 2008
 
ABBVIE DEUTSCHLAND GMBH & CO. KG (2)
8895004 Method for the treatment of amyloidoses 0 2008
9176150 Amyloid beta(1-42) oligomers, derivatives thereof and antibodies thereto, methods of preparation thereof and use thereof 0 2011
 
UNIVERSITY OF SOUTH FLORIDA (1)
8188046 Amyloid beta peptides and methods of use 0 2007
 
H. LUNDBECK A/S (3)
* 2009/0092,579 NOVEL METHOD FOR DOWN-REGULATION OF AMYLOID 1 2008
8871212 Amyloid-beta polypeptide vaccine 0 2008
* 2010/0047,262 NOVEL METHOD FOR DOWN-REGULATION OF AMYLOID 0 2008
 
ABBVIE INC. (9)
8691224 Anti-Aβ globulomer 5F7 antibodies 2 2006
8497072 Amyloid-beta globulomer antibodies 0 2006
8455626 Aβ conformer selective anti-aβ globulomer monoclonal antibodies 0 2007
8987419 Amyloid-beta binding proteins 0 2011
8877190 Aβ conformer selective anti-Aβ globulomer monoclonal antibodies 0 2011
9062101 Amyloid-beta binding proteins 0 2011
9359430 Abeta conformer selective anti-Abeta globulomer monoclonal antibodies 0 2013
9540432 Anti-Aβ globulomer 7C6 antibodies 0 2013
9394360 Aβ conformer selective anti-Aβ globulomer monoclonal antibodies 0 2014
 
NEW YORK UNIVERSITY (3)
* 8685718 Mucosal immunization to prevent prion infection 0 2004
* 2007/0059,807 Mucosal immunization to prevent prion infection 3 2004
* 9700607 Mucosal immunization to prevent prion infection 0 2014
* Cited By Examiner

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