Crystals of an acyl carrier protein synthase/acyl carrier protein complex
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United States of America Patent
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Nov 14, 2006
Grant Date -
Apr 22, 2004
app pub date -
Nov 19, 2003
filing date -
May 8, 2000
priority date (Note) -
Expired
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Abstract
This invention is directed to the crystal structure of Acyl Carrier Protein Synthase (ACPS) complexed with Acyl Carrier Protein (ACP), the solution structure of B. subtilis ACP, and to the use of these structures in rational drug design methods to identify agents that may interact with active sites of ACPS and ACP, and to the testing of these agents to identify agents that may represent novel antibiotics.
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