Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
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United States of America Patent
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Nov 21, 2006
Grant Date -
Oct 31, 2002
app pub date -
Dec 10, 2001
filing date -
Feb 13, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
An iontophoretic method for transporting compounds of interest across a body tissue is provided. The method utilizes an AC signal in conjunction with a barrier-modifying agent such as a fatty acid, fatty alcohol, bile acid, surfactant, or the like. The method enables the maintenance of a substantially constant electrical state in a localized region of the tissue through which transport occurs, thereby allowing a compound of interest to be transported across the tissue in a controlled and predictable manner. The barrier-modifying agent reduces the time as well as the voltage level required to achieve a target electrical resistance, thereby reducing patient discomfort and increasing the battery life of the iontophoresis device.
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