Methods of treating rheumatoid arthritis with anti-TNF antibodies

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United States of America Patent

PATENT NO 7138118
APP PUB NO 20060121037A1
SERIAL NO

11297810

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-.alpha. (TNF.alpha.) and are useful in vivo diagnosis and therapy of a number of TNF.alpha.-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.

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Patent Owner(s)

  • CENTOCOR, INC.;NEW YORK UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Daddona, Peter Menlo Park, CA 59 1770
Ghrayeb, John Thorndale, PA 68 2681
Knight, David Berwyn, PA 135 4072
Le, Junming Jackson Heights, NY 59 2436
Siegel, Scott Westborough, MA 46 1466
Vilcek, Jan New York, NY 54 2057

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