Diagnostics based on tetrazolium compounds

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United States of America Patent

PATENT NO 7144709
SERIAL NO

10990684

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Abstract

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A reagent is suitable for measuring the concentration of an analyte in a hemoglobin-containing biological fluid, such as whole blood. The reagent comprises a flavin-dependent enzyme that has specificity for the analyte, a flavin cofactor if, and only if, a flavin is not bound to the enzyme, a tetrazolium dye precursor, an electron transfer agent, and a nitrite salt. The reagent causes dye formation that is a measure of the analyte concentration. The nitrite salt suppresses interfering dye formation caused non-enzymatically by the hemoglobin. Preferably, the reagent is used in a dry strip for measuring glucose in whole blood.

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Patent Owner(s)

Patent OwnerAddress
ANKURA TRUST COMPANY LLC AS SUCCESSOR AGENT140 SHERMAN STREET 4TH FLOOR FAIRFIELD CT 06824

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ouyang, Tianmei Fremont, CA 92 3027
Yu, Yeung Siu Pleasanton, CA 18 2222

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