Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
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United States of America Patent
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Dec 12, 2006
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N/A
app pub date -
May 6, 2004
filing date -
Dec 29, 2000
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Abstract
This invention is for an improved process to formulate polymeric microspheres/nanospheres and encapsulate therapeutic proteins and other useful substances. Non-toxic supercritical or near-critical fluids with/without polar cosolvents are utilized to solubilize biodegradable polymers and form uniform polymer microspheres and nanospheres to encapsulate proteins with controlled-release characteristics.
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